Cognition. The rate of synaesthesia in adults with autism was 18.9% (31 out of 164), almost three times greater than in controls (7.22%, 7 out of 97, P <0.05). I think what you describe has a different name. Some of the websites I've been reading.they're fascinated with the idea of mirror-touch synesthesia being a form of empathy that might help in understanding autism. . Psychophysical investigations into the neural basis of synaesthesia. Before A Close Look at The Most Common Types of Synesthesia . According to one hypothesis, autism is associated with a reduction in long-range neural connections, alongside an increase in local, short-range connectivity [3, 4]. CAS Nat Neurosci. MeSH Brain. This was used to validate any self-reported auditory-visual forms of grapheme-colour (GC) and sound-colour (SC) synaesthesia and was sent to all participants in order to detect true and false positives and negatives. The total number of actual points was divided by the total number of possible points. This article is published under license to BioMed Central Ltd. Bogdashina O: Sensory Perceptual Issues in Autism: Different Sensory Experiences- Different Perceptual Worlds. Synesthesia is a condition in which one sense (hearing, sight, smell, sound, taste) is simultaneously and spontaneously perceived as if by one or more additional senses. Familial patterns and the origins of individual differences in synaesthesia. Conservative inclusion criteria were used to judge if any individual had synaesthesia. The .gov means its official. * Prevalence of PDD-NOS (now call. PubMed 10.1016/j.jneumeth.2006.07.012. The new PMC design is here! Fourth, it would be interesting to test how people with autism and synaesthesia differ from those with autism alone. There are several limitations of this study. 2011, 9 (6): e1001081-10.1371/journal.pbio.1001081. Baron-Cohen S, Wyke M, Binnie C: Hearing words and seeing colours: an experimental investigation of a case of synaesthesia. 2021 Feb;22(1):1-36. doi: 10.1007/s10339-020-00992-6. 2003, 290: 337-344. will also be available for a limited time. Google Scholar. This is an open access article distributed under the terms of the Creative Commons Attribution License (. PubMed Central Cesaroni L, Garber M. Exploring the experience of autism through first-hand accounts. The hyper-connectivity hypothesis proposes that people with synaesthesia have excessive neural connections between different regions, connections that are diminished or absent from unaffected individuals [5, 1921]. In order to reduce sampling bias, the consent form stressed that all individuals with autism or synaesthesia, both, or neither were eligible to participate. 1991, 21: 303-313. 2009, 194: 500-509. Synesthesia is a neurological condition in which information meant to stimulate one of your senses stimulates several of your senses. Neuroimaging studies of autism indicate that the autistic brain is anatomically and functionally different from the typical brain [3, 23, 24]. It may be the case that traditional ToGs are not suitable for people with autism and that these will require modification. Synaesthesia and cortical connectivity. In the present study, we carried out the first direct assessment of overlap between the two conditions. Google Scholar, Baron-Cohen S: Is there a phase of synaesthesia in normal development?. The email defined and briefly described synaesthesia; the definition of synaesthesiaawas provided in the informed consent form. J Amer Med Assoc. The scientists tested and confirmed the prediction that if both autism and synaesthesia involve neural over-connectivity, then synaesthesia might be disproportionately common in autism. Sensory Perceptual Issues in Autism: Different Sensory Experiences- Different Perceptual Worlds. A related possible explanation of the comorbid association might be failure in inhibition/greater cortical excitation [42]. Second, response rates to the initial invitations were low, which is not unusual in survey research [45], therefore, other studies must become available to confirm the observed synaesthesia prevalence rates observed, and extrapolation from the current study should be done with caution until other such surveys have been conducted. Tables2and 3show an overview of what types of synaesthesia were reported in each group, and Table4shows the number of participants with any type of synaesthesia who completed a GC ToG-R and/or a SC ToG-R. But at the level of the brain, synaesthesia involves atypical connections between brain areas that are not usually wired together (so that a sensation in one channel automatically triggers a perception in another). Cortical activation and synchronizatioin during sentence comprehension in high-functioning autism: evidence of underconnectivity. An example is the mechanism 'apoptosis,' the natural pruning that occurs in early development, where we are programmed to lose many of our infant neural connections. Please enable it to take advantage of the complete set of features! Results: The rate of synaesthesia in adults with autism was 18.9% (31 out of 164), almost three times greater than in controls(7.22%, 7 out of 97, P 0.05). Crucially, people with developmental synaesthesia describe their experiences as automatic and involuntary, in contrast to metaphoric associations that are voluntary and are not intended to be taken literally [14]. The Following that, there is a list of people who are often wrongly believed to have had synesthesia because they used it as a device in their art, poetry or music (referred to as pseudo-synesthetes). Third, this question has not yet been tested in different clinical groups to assess if this link is specific to autism. Yes, this is kind of a large range. Language evolution: examining the link between cross-modality and aggression through the lens of disorders. Familial patterns and the origins of individual differences in synaesthesia. Epub 2019 Oct 21. 8600 Rockville Pike Hum Mol Genet. Neurocase. 2008, 31: 335-342. The trouble is, none of these things are new to the world, either. bTo be considered synaesthetic, participants had to report that they experienced synaesthesia and could not meet any of the exclusion criteria (see Methods). 1997, Malden: Blackwell Publishing. 10.1192/bjp.bp.108.059345. Interestingly, synesthesia is more common in individuals with Autism Spectrum Disorder (ASD) [ 24 - 26 ]. The aim of the current pilot study was to test this hypothesis by investigating a group of patients diagnosed with Asperger Syndrome (AS) using questionnaires and standard consistency tests in order to classify them as grapheme-color synaesthetes. A whole-genome scan and fine-mapping linkage study of auditory-visual synesthesia reveals evidence of linkage to chromosomes 2q24, 5q33, 6p12, and 12p12. Rich AN, Bradshaw JL, Mattingley JB. Disclaimer, National Library of Medicine As Figure2shows, there is no overlap in the rates of synaesthesia in autism vs. controls. Synaesthesia occurs when the stimulation of one sensory modality automatically evokes a perception in another unstimulated modality [6]. Tables2 and and33 show an overview of what types of synaesthesia were reported in each group, and Table4 shows the number of participants with any type of synaesthesia who completed a GC ToG-R and/or a SC ToG-R. Correspondence to The study was approved by the Psychology Research Ethics Committee of the University of Cambridge. However, most studies have relied on synesthetes . People who have any type of synesthesia tend to have these common symptoms: involuntary perceptions that cross over between senses . In the autism group, n = 9 (5.5%) had high functioning autism, n = 153 (93%) had Asperger syndrome, and n = 2 (1.2%) had pervasive developmental disorder, not otherwise specified. PLoS ONE. Privacy Genes play a substantial role in autism and scientists have begun to pinpoint some of the individual genes involved. DSM-IV Diagnostic and Statistical Manual of Mental Disorders. www.sciencedaily.com/releases/2013/11/131119193908.htm (accessed November 3, 2022). Mirror-Touch Synesthesia. SBC and DJ drafted the manuscript and SEF, JA, and PG contributed to the manuscript. Atypical sensory sensitivity as a shared feature between synaesthesia and autism. smell colours. 2009, 132: 57-64. The idea has tentative indirect support from two different lines of investigation. First, we were unable to collect complete consistency tests to validate the prevalence estimates, which will be important to explore in future work. As autism, synesthesia can be described as a spectrum with some 'weak' forms, which are common, and some less common cases possessing strong, reliable, complex, or multiple forms of synesthesia. Participants are asked to choose from a colour chart to indicate the closest match evoked by a word (GC) or a sound (SC), and are then re-tested after an interval of at least a month, without warning. Ten percent of individuals with autism have savant skills (a skill that is above average for the general population), and an estimated 50% of savants have autism [27]. However, up to now a systematic investigation of whether synesthesia is more common in ASC patients is missing. Dohn A, Garza-Villarreal E, Heaton P, Vuust P: Do musicians with perfect pitch have more autism traits than musicians without perfect pitch? Our selection of the week's biggest Cambridge research news and features sent directlyto your inbox. 2013, 22 (10): 2097-2104. As stated above, 172 adults with autism and 123 typical adults responded and gave electronic consent. Can synaesthesia research inform cognitive science? Molecular Autism Only about one to four percent of the general population experience this phenomenon. Cytowic corroborates that "synesthesia is more common among artists than it is among the general population.". If you use this content on your site please link back to this page. Riedel A, Maier S, Wenzler K, Feige B, Tebartz van Elst L, Blte S, Neufeld J. BMC Psychiatry. (2006) [32]. Perception. Our findings indicate that synaesthesia is significantly more common in adults with autism than in typical adults, based on self-report. J Autism Dev Disord. Previous work has found that synaesthetes far out-perform controls in the consistency across time in their colour reports to specific stimuli. 2004, 24: 9228-9231. Interestingly, a recent study has revealed a significant phenotypic and genetic overlap between synaesthesia and absolute pitch [38], a trait that has also been reported to occur at increased frequency in people with autism [39,40]. This work was submitted in part fulfilment of the degree of Master of Philosophy by DJ. As Figure2 shows, there is no overlap in the rates of synaesthesia in autism vs. controls. We are committed to protecting your personal information and being transparent about what information we hold. Autism (shorthand for Autism Spectrum Conditions) is a neurodevelopmental condition involving social-communication disability alongside resistance to change and unusually narrow interests or activities. Daniel Tammet, who has both Asperger syndrome and synaesthesia, and who is a memory savant (he memorized Pi to 22,514 decimal places) inspired the hypothesis that savantism arises in individuals who have both autism and synaesthesia. In the present study, we carried out the first direct assessment of overlap between the two conditions. taste shapes. Correlations among synesthesia, autism, and transgenderism Synesthesia is more common in individuals with autism.1,14Individuals with autism are also more likely to be transgender or gender variant.15-17No studies could be found discussing whether synesthesia and transgenderism are correlated. Courchesne, Carper R, Akshoomoff NA. However, these genetic findings may not overlap since the study by Asher et al. What causes grapheme-color synesthesia? A related possible explanation of the comorbid association might be failure in inhibition/greater cortical excitation [42]. PubMedGoogle Scholar. Questions? In number form . The team of scientists from Cambridge University found that whereas synaesthesia only occurred in 7.2% of typical individuals, it occurred in 18.9% of people with autism. The new neurobiology of autism: cortex, connectivity, and neuronal organization. This is the total number of possible points on the test (e.g., if a person gave valid answers for all 99 sounds, the total number of points possible would be 297). Since synesthesia is a neurodivergence, there are no neurotypical people with it by definition. Bethesda, MD 20894, Web Policies 2001, 268: 979-983. Autism, autistic traits and creativity: a systematic review and meta-analysis. People who report a lifelong history of such experiences are known as synesthetes.Awareness of synesthetic perceptions varies from person to person. I wish to receive a weekly Cambridge research news summary by email. (2008a). . Psychol Sci. The most common forms of synaesthesia involve written and/or auditory stimuli triggering colours [1, 7]. Autism is diagnosed when a person struggles with social relationships and communication, and shows unusually narrow interests and resistance to change. Although it is true that adults with autism score highly on sensory sensitivity questionnaires [41], we doubt this can explain the current results, because our sample included some individuals with autism (n = 3) who claimed they did not have synaesthesia, but were judged by the experimenters to have synaesthesia on the basis of their questionnaire responses. Kemner C, Verbaten MN, Cuperus JM, Camfferman G, van Engeland H. Auditory event-related brain potentials in autistic children and three different control groups. Studies have suggested, as he noted in a 2014 article, "that people with synesthesia do have enhanced creative abilities, creative cognition.". 1995, 38: 150-165. Recent studies suggest that savantism is, in some form, a . Kemner C, Verbaten MN, Cuperus JM, Camfferman G, van Engeland H: Auditory event-related brain potentials in autistic children and three different control groups. 10.1016/j.ajhg.2009.01.012. 2019 Dec 9;374(1787):20190024. doi: 10.1098/rstb.2019.0024. Consistency scores were based on a point system created by Asher et al. Twenty-six of the typical adults were excluded for scoring >25 on the AQ, leaving a final non-autistic group of n = 97. 2009, 364: 1351-1357. * * Addressing the limitations of the study. -. The scientists tested -- and confirmed -- the prediction that if both autism and synaesthesia involve neural over-connectivity, then synaesthesia might be disproportionately common in autism. 2001, 57: 245-254. Pennisi P, Giallongo L, Milintenda G, Cannarozzo M. Cogn Process. The team of scientists from Cambridge University found that whereas synaesthesia only occurred in 7.2% of typical individuals, it occurred in 18.9% of people with autism. Sperling JM, Prvulovic D, Linden DEJ, Singer W, Stirn A. Neuronal correlates of colour-graphemic synaesthesia: a fMRI study. Simner J, Mulvenna C, Sagiv N, Tsakanikos E, Witherby SA, Fraser C, Scott K, Ward J. Synaesthesia: the prevalence of atypical cross-modal experiences. Most importantly, the next step in future research must be to explore the biological mechanisms causing the elevated rate of synaesthesia in autism. Although it is true that adults with autism score highly on sensory sensitivity questionnaires [41], we doubt this can explain the current results, because our sample included some individuals with autism (n = 3) who claimed they did not have synaesthesia, but were judged by the experimenters to have synaesthesia on the basis of their questionnaire responses. Synaesthesia involves people experiencing a 'mixing of the senses', for example, seeing colours when they hear sounds, or reporting that musical notes evoke different tastes. Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough (CLAHRC CP). Interestingly, a recent study has revealed a significant phenotypic and genetic overlap between synaesthesia and absolute pitch [38], a trait that has also been reported to occur at increased frequency in people with autism [39, 40]. Nat Neurosci. This strengthens the case that autism and synaesthesia are linked at multiple levels. California Privacy Statement, Simner J, Mulvenna C, Sagiv N, Tsakanikos E, Witherby SA, Fraser C, Scott K, Ward J: Synaesthesia: the prevalence of atypical cross-modal experiences. The rate of synaesthesia in autism (18.9%) was almost three times greater than in the typical sample (7.22%), whose rate overlaps with the 4% reported previously (given confidence intervals) [1]. But among people with autism spectrum disorders, the condition might. The Test of Genuineness-Revised (ToG-R) [32]. On the face of it, this is an unlikely result, as autism and synaesthesia seem as if they should not share anything. Scoring protocol for the ToG-R. Each box represents a swatch on the colour chart. [32] (Figure1). Perception. Evidence for this hypothesis comes from a diffusion tensor imaging study [18] showing that people with grapheme-colour synaesthesia have increased white matter connectivity compared to unaffected controls. Developmental synaesthesia is distinct from acquired synaesthesia where individuals report first experiencing synaesthesia later in life, after an inducing event such as the use of hallucinogenic drugs [12]. Participants are asked to choose from a colour chart to indicate the closest match evoked by a word (GC) or a sound (SC), and are then re-tested after an interval of at least a month, without warning. The rate of synaesthesia in autism (18.9%) was almost three times greater than in the typical sample (7.22%), whose rate overlaps with the 4% reported previously (given confidence intervals) [ 1 ]. The hyper-connectivity hypothesis proposes that people with synaesthesia have excessive neural connections between different regions, connections that are diminished or absent from unaffected individuals [5,19-21]. Cite this article. Participants (aged 18 years old or older) were invited to visit one of two websites (http://www.autismresearchcentre.com or http://www.cambridgepsychology.com) hosted by the Autism Research Centre at Cambridge University. Some people even experience more than one type of synaesthesia. A person with synaesthesia can: see sounds. The site is secure. Beyond such single-case reports of synaesthesia in autism, it has been proposed that synaesthesia may be common in autism [29,30]. Synesthesia is a condition caused by a genetic mutation that leads to stronger connections between certain parts of the brain. It is not a surprise that synesthesia may be more common among people in the autism-spectrum. In both autism and synaesthesia apoptosis may not occur at the same rate, so that these connections are retained beyond infancy. Perceptual Gains and Losses in Synesthesia and Schizophrenia. 2008, 106: 871-893. "Wednesdays are always blue, like the number nine or the sound of loud voices arguingTuesdays are a warm colour while Thursdays . Famous people with synesthesia disorder include Billy Joel, Marilyn Monroe, Itzhak Perlman, Duke Ellington, Nikola Tesla, Mickey Hart (The Grateful Dead drummer), and Vincent Van Gogh. There was a difference in handedness and in sex ratio, in line with previous studies of autism (both P<0.05) [34, 35]. Witthoft N, Winawer J: Learning, memory, and synesthesia. 2000, Washington, DC: APA, 4. 2021. van Leeuwen TM, Sauer A, Jurjut AM, Wibral M, Uhlhaas PJ, Singer W, Melloni L. Schizophr Bull. If these conditions are independent, then synaesthesia and autism should co-occur in only 4 in 10,000 people. The Animal Welfare and Ethical Review Body, Report on the allegations and matters raised in the BUAV report, Non-human primates (marmosets and rhesus macaques). This new study goes one step further in identifying synaesthesia as a sensory issue that has been overlooked in this population. Crucially, people with developmental synaesthesia describe their experiences as automatic and involuntary, in contrast to metaphoric associations that are voluntary and are not intended to be taken literally [14]. Hey u/Kitkat_Zap9, thank you for your post at r/autism. The team of scientists from Cambridge University found that whereas synaesthesia only occurred in 7.2% of typical individuals, it occurred in 18.9% of people with autism. ScienceDaily, 19 November 2013. Professor Baron-Cohen said: "I have studied both autism and synaesthesia for over 25 years and I had assumed that one had nothing to do with the other. How Is Synesthesia Diagnosed? Treffert DA. Am. Belmonte MK, Allen G, Beckel-Mitchener A, Boulanger LM, Carper R, Webb SJ. Bor D, Billington J, Baron-Cohen S: Savant memory for digits in a case of synaesthesia and asperger syndrome is related to hyperactivity in the lateral prefrontal cortex. https://creativecommons.org/licenses/by/2.0 . 196, 565571 10.1007/s00221-009-1888-0 government site. An example of the latter is the link between post-traumatic stress disorder (PTSD) and Grapheme-color Synesthesia, one of the more common forms of synesthetic perception. Commenting on the research, Prof Ward said: "Synaesthesia has traditionally been considered more of a gift than an impairment, whereas the opposite could often be said of autism. Hoffman SN, Zhang X, Erlich PM, Boscarino JA. This new research gives us an exciting new lead, encouraging us to search for genes which are shared between these two conditions, and which might play a role in how the brain forms or loses neural connections. aSynaesthesia is a condition in which a sensation in one sensory modality automatically triggers a response in a different sensory modality. Synesthesia the mysterious phenomenon of "mixed senses" is thought to affect a small fraction of the general population. 10.1001/jama.290.3.337. HHS Vulnerability Disclosure, Help People who have synesthesia are called synesthetes. 2009, 84: 279-285. Cortex. Akshoomoff N, Pierce K, Courchesne E. The neurobiological basis of autism from a developmental perspective. This finding is discussed in relation to different theories regarding the development of synesthesia as well as altered sensory processing in autism. Heredity in Synesthesia 10.1016/j.cub.2011.10.032. However, up to now a systematic investigation . The authors declare no competing interests. Accessibility Developmental Neurocognition: Speech and Face Processing in the First Year of Life. Edited by: Tager-Flusberg H. 1999, Cambridge, MA: MIT Press. Autism has also been postulated to involve over-connectivity of neurons (so that the person over-focuses on small details but struggles to keep track of the big picture). Eight of the adults with autism were excluded for reporting a self- but not clinician-diagnosed autism. 8600 Rockville Pike Grapheme-color synesthesia is a harmless, alternative form of perception caused by subtle differences in the brain -- possibly, stronger connections between centers for language and color -- that give letters and numbers their phantom colors. This new study goes one step further in identifying synaesthesia as a sensory issue that has been overlooked in this population. Developmental synaesthesia is not easily explained by learning because siblings with this condition, exposed to similar environments, often report different colours for the same inducer, or experience different variants of the trait [10], although this has been disputed [13]. This was used as a further form of self-report of synaesthesia and to document the subtype(s) experienced. Autism (shorthand for Autism Spectrum Conditions) is a neurodevelopmental condition involving social-communication disability alongside resistance to change and unusually narrow interests or activities. University of Cambridge. Synesthesia is more common among aspies than in the general population, it seems. An increased connectivity in the brain was also found within synesthetes. Future research needs to develop more feasible validation methods of synaesthesia in autism. S2 ep2: What did the future look like in the past? Tavassoli T, Auyeung B, Murphy L, Baron-Cohen S, Chakrabarti B. 10.1016/j.cognition.2004.11.003. statement and Neuroimaging studies of autism indicate that the autistic brain is anatomically and functionally different from the typical brain [3,23,24]. Note: Content may be edited for style and length. 2019. Synesthesia is thought to be more common in people with autism (Alex has been diagnosed with pervasive developmental disorder-not otherwise specified, a form of autism with milder symptoms), and in creative people, including artists, musicians, and poets. Participants (aged 18 years old or older) were invited to visit one of two websites (http://www.autismresearchcentre.comor http://www.cambridgepsychology.com) hosted by the Autism Research Centre at Cambridge University. Content on this website is for information only. This was used to measure the number of autistic traits, as a check on an autism diagnosis. Among the 31 people with autism who also had synaesthesia, the most common forms of the latter were 'grapheme-colour' (18 of them reported black and white letters being seen as coloured) and 'sound-colour' (21 of them reported a sound triggering a visual experience of colour). PubMed 10.1016/j.neuron.2005.10.012. Clipboard, Search History, and several other advanced features are temporarily unavailable. In total, 172 adults with autism and 123 typical adults responded and gave electronic consent. If these conditions are independent, then synaesthesia and autism should co-occur in only 4 in 10,000 people. 2005, 98: 53-84. ASD is a neurodevelopmental condition with a prevalence of 1-2.6% [ 27, 28 ], characterized by impairing patterns of social communication and interaction alongside restricted/repetitive patterns of behavior, interests, or activities [ 29 ]. The ToG-R is a colour chart that measures consistency in a participants reported colour associations to either letters (GC) or sounds (SC) over time. ToG-R proved unsuitable for synaesthetes with autism. V6 "',' N q-]Sl(' 8 ) / dfv.,A?4JU r |"-Gl |GN8+K|si?g{p' ^} O R 6 /&Rb#D u16 6d > % z gGcv [S} 6-oU _.#{F[gGdw@7-E M . Synesthesia is more common in people with autism as well as artistic people, including visual artists, musicians, and actors. However, both are thought to involve atypical neural connectivity [3-5], which may point to a shared aetiology. Diagnostic and Statistical Manual of Mental Disorders. But at the level of the brain, synaesthesia involves atypical connections between brain areas that are not usually wired together (so that a sensation in one channel automatically triggers a perception in another). Ramachandran VS, Hubbard EM: Psychophysical investigations into the neural basis of synaesthesia. Autism (shorthand for Autism Spectrum Conditions) is a neurodevelopmental condition involving social-communication disability alongside resistance to change and unusually narrow interests or activities. Gregersen P, Kowalsky E, Lee A, Baron-Cohen S, Fisher S, Asher J, Ballard D, Freudenberg J, Li W: Absolute pitch exhibits phenotypic and genetic overlap with synesthesia. ago Yeah same. Estimates of prevalence of synesthesia have ranged widely, from 1 in 4 to 1 in 25,000 - 100,000. A whole-genome scan and fine-mapping linkage study of auditory-visual synesthesia reveals evidence of linkage to chromosomes 2q24, 5q33, 6p12, and 12p12. color or texture. Beyond such single-case reports of synaesthesia in autism, it has been proposed that synaesthesia may be common in autism [29, 30]. Living with Synesthesia 1Autism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B Trumpington Rd, Cambridge CB2 8AH, UK, 2Max Planck Institute for Psycholinguistics, 6500 AH, Nijmegen, The Netherlands, 3Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands, 4Robert S. Boas Center for Genomics and Human Genetics, The Feinstein Institute for Medical Research, North Shore-LIJ, Manhasset 11030, NY, USA. . Synaesthesia involves people experiencing a mixing of the senses, for example, seeing colours when they hear sounds, or reporting that musical notes evoke different tastes. 2007, 11: 177-184. Cesaroni L, Garber M: Exploring the experience of autism through first-hand accounts. 10.1007/BF02207327. Brain. Baron-Cohen S, Bor D, Billington J, Asher J, Wheelwright S, Ashwin C. Savant memory in a man with colour-number synaesthesia and Asperger Syndrome. Synesthesia is a condition in which one sense (for example, hearing) is simultaneously perceived as if by one or more additional senses such as sight. However, both are thought to involve atypical neural connectivity [35], which may point to a shared aetiology. Hubbard EM, Ramachandran VS: Neurocognitive mechanisms of synesthesia. Baron-Cohen S, Burt L, Laittan-Smith F, Harrison JE, Bolton P: Synaesthesia: prevalence and familiarity. People who have the characteristics of super high intelligence are more likely to have synesthesia. Simon Baron-Cohen, Donielle Johnson, Julian Asher, Sally Wheelwright, Simon E Fisher, Peter K Gregersen, Carrie Allison. SBC, DJ, SW, and CA designed the study. Future research is needed to develop more feasible validation methods of synaesthesia in autism. The rate of synaesthesia in autism (18.9%) was almost three times greater than in the typical sample (7.22%), whose rate overlaps with the 4% reported previously (given confidence intervals) [1]. volume4, Articlenumber:40 (2013) The question of a continuum between multimodal association and synesthesia, the latter falling at the extreme end of continuum, is an ongoing . A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p.
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